Webmd explains the benefits and disadvantages of long acting schizophrenia or antipsychotic drugs that you take as a shot once or twice a month. They used to be called depot antipsychotics but the powers that be have renamed them long acting injectables lais presumably to help remove some of the stigma associated with their . Long acting injectables lais are unique tools used in psychiatric pharmacy to help improve patient outcomes they offer a number of benefits compared to oral therapy including confirmed patient adherence consistent drug delivery predictable bioavailability and prevention of antipsychotic overdoses. Poor adherence to antipsychotic therapy is an important factor that contributes to possible inadequacy of treatment a considerable ef fort has been put into the development of antipsychotic drugs with better toler ability or in formulations that enable less frequent administration including long acting injectable lai antipsychotics
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